Cysteinyl-leukotrienes and the liver

被引：21

作者：

Farzaneh-Far, R ^{[1
]}

Moore, K ^{[1
]}

机构：

[1] UCL Royal Free & Univ Coll, Sch Med, Dept Med, Ctr Hepatol, London NW3 2PF, England

来源：

PROSTAGLANDINS & OTHER LIPID MEDIATORS | 2003年 / 72卷 / 1-2期

关键词：

leukotrienes; liver; hepatitis; cirrhosis; hepatorenal; cholestasis;

D O I：

10.1016/S1098-8823(03)00076-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Leukotrienes are potent biological mediators implicated in an increasing number of disease processes. This review outlines the basic biology of leukotrienes and discusses recent developments in our understanding of the specific role of cysteinyl-leukotrienes (cLTs) in cholestasis, hepatic inflammation, portal hypertension, and the pathogenesis of the hepatorenal syndrome (HRS). (C) 2003 Published by Elsevier Inc.

引用

页码：35 / 50

页数：16

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