Cytostatic activity of some compounds from the unsaponifiable fraction obtained from virgin olive oil

被引：24

作者：

Saenz, MT ^{[1
]}

Garcia, MD

Ahumada, MC

Ruiz, V

机构：

[1] Univ Sevilla, Fac Farm, Lab Farmacognosia, E-41012 Seville, Spain

[2] CSIC, Inst Grasa, E-41080 Seville, Spain

来源：

FARMACO | 1998年 / 53卷 / 06期

关键词：

olive oil; cytostatic activity; oleuropein; tyrosol; sterols;

D O I：

10.1016/S0014-827X(98)00043-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Oleuropein, tyrosol, squalene and the fraction of sterols and triterpenoid dialcohols from the unsaponifiable fraction obtained from virgin olive oil have been tested for its possible cytostatic activity against McCoy cells, using 6-mercaptopurine as a positive control. The samples of sterols and triterpenic dialcohols showed a strong activity. (C) 1998 Elsevier Science S.A. All rights reserved.

引用

页码：448 / 449

页数：2

共 17 条

[1] BORS W, 1990, FREE RADICALS LIPOPR
[2] BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
[3] CYTOSTATIC AND ANTIBACTERIAL ACTIVITY OF SOME COMPOUNDS ISOLATED FROM SEVERAL LAMIACEAE SPECIES FROM THE CANARY ISLANDS
DARIAS, V
BRAVO, L
RABANAL, R
SANCHEZMATEO, CC
MARTINHERRERA, DA
[J]. PLANTA MEDICA, 1990, 56 (01) : 70 - 72
[4] Duthie G G, 1989, Nutr Res Rev, V2, P51, DOI 10.1079/NRR19890007
[5] GERAN RI, 1972, CANCER CHEMOTHERAPY, V3, P17
[6] Gomez MA, 1997, PHYTOTHER RES, V11, P240, DOI 10.1002/(SICI)1099-1573(199705)11:3<240::AID-PTR54>3.0.CO
[7] 2-K
[8] GRACIAN T, 1986, ANAL CHARACTERIZATIO
[9] PLANT ANTICANCER AGENTS .50. CYTOTOXIC TRITERPENES FROM SANDORICUM-KOETJAPE STEMS
KANEDA, N
PEZZUTO, JM
KINGHORN, AD
FARNSWORTH, NR
SANTISUK, T
TUCHINDA, P
UDCHACHON, J
REUTRAKUL, V
[J]. JOURNAL OF NATURAL PRODUCTS, 1992, 55 (05): : 654 - 659
[10] STUDIES ON INDONESIAN MEDICINAL-PLANTS .2. CYTOTOXIC CONSTITUENTS OF THE BARK OF PLUMERIA-RUBRA COLLECTED IN INDONESIA
KARDONO, LBS
TSAURI, S
PADMAWINATA, K
PEZZUTO, JM
KINGHORN, AD
[J]. JOURNAL OF NATURAL PRODUCTS, 1990, 53 (06): : 1447 - 1455

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