Bactericidal activities of antibiotics against intracellular Francisella tularensis

被引：50

作者：

Maurin, M ^{[1
]}

Mersali, NF ^{[1
]}

Raoult, D ^{[1
]}

机构：

[1] Univ Mediterranee, Fac Med, CNRS UPRESA 6020, Unite Rickettsies, F-13385 Marseille 05, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2000年 / 44卷 / 12期

关键词：

D O I：

10.1128/AAC.44.12.3428-3431.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

MICs of many antibiotics for Francisella tularensis are low in axenic medium, whereas only aminoglycosides, tetracyclines, and fluoroquinolones are useful in treating tularemic patients. In an in vitro cell system, only these antibiotics, rifampin, and telithromycin were bactericidal against intracellular F. tularensis. These results correlate better with clinical data than MIC data do.

引用

页码：3428 / 3431

页数：4

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