Resorption kinetics of osseous substitute: Natural coral and synthetic hydroxyapatite

被引：50

作者：

Braye, F

Irigaray, JL

Jallot, E

Oudadesse, H

Weber, G

Deschamps, N

Deschamps, C

Frayssinet, P

Tourenne, P

Tixier, H

Terver, S

Lefaivre, J

Amirabadi, A

机构：

[1] UNIV CLERMONT FERRAND,F-63177 CLERMONT FERRAN,FRANCE

[2] INST PHYS NUCL EXPT,B-4000 LIEGE,BELGIUM

[3] LAB PIERRE SUE,F-91190 GIF SUR YVETTE,FRANCE

[4] SOC IND BIOLAND,F-31100 TOULOUSE,FRANCE

[5] SERV PROFESSEUR TERVER,F-63000 CLERMONT FERRAN,FRANCE

[6] INRA,F-63122 ST GENES CHAMPANE,FRANCE

[7] ATOM ENERGY ORG IRAN,TEHRAN,IRAN

来源：

BIOMATERIALS | 1996年 / 17卷 / 13期

关键词：

bone substitutes; interface; biomaterial resorption; coral; hydroxyapatite;

D O I：

10.1016/0142-9612(96)88682-0

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Coral and hydroxyapatite may be used as substitution biomaterials for bone grafts. In this work, we extracted the implants from the femora to study the kinetics of elementary mineral transformation of the osseous substitutes. The use of physical analysis methods such as PIXE (particle-induced X-ray emission) shows that coral and hydroxyapatite, after their implantation in vivo, reach a mineral composition comparable with that of bone. For the first time we have measured the concentration of mineral elements, at different time intervals after implantation, along a cross-section. The distribution according to mineral elements (Ca, P, Sr, Zn, Fe) in the implant, in the receiver site and also at the interface, showed that the kinetics of coral resorption was faster than that of hydroxyapatite; in the same way, the osseous attack was not global but, rather, centripetal. (C) 1996 Elsevier Science Limited

引用

页码：1345 / 1350

页数：6