The impact of endocrine disrupters on the female reproductive system

被引:85
作者
Nicolopoulou-Stamati, P [1 ]
Pitsos, MA [1 ]
机构
[1] Univ Athens, Sch Med, Dept Pathol, GR-11527 Athens, Greece
关键词
endocrine disrupters; endometriosis; female hormones; pesticides; reproduction;
D O I
10.1093/humupd/7.3.323
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Over the last decades, many tonnes of man-made chemicals have been produced and released into the environment, Many of these chemical substances have the ability to modulate the action of hormones and are called endocrine disrupters. Cell receptors that have been pure receptors for thousands of years have (due to industrialization), become susceptible to the action of exogenous chemicals. The balance of the endocrine system is very important in the human body especially in females because the menstrual cycle and fertility are very sensitive to hormone imbalances, This review considers the mode of exposure and action of endocrine disrupters and focuses on their impact on the female reproductive system, including female hormone concentrations, menstrual cycle, fertility, spontaneous abortion and the development of endometriosis, An attempt is made to elucidate the impact of endocrine disrupters on the female reproductive system, while admitting that most scientific data come from experimental animals and the conclusions cannot be applied to humans easily. The aim is to present available information, highlighting the impact of endocrine disrupters on the female reproductive system, in order to stimulate reevaluation in identifying hormone disorders.
引用
收藏
页码:323 / 330
页数:8
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