Iron status of breast-fed infants

被引:89
作者
Dewey, Kathryn G. [1 ]
Chaparro, Carnila M. [1 ]
机构
[1] Univ Calif Davis, Program Int & Community Nutr, Dept Nutr, Davis, CA 95616 USA
关键词
D O I
10.1017/S002966510700568X
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Fe deficiency is a common nutritional disorder during infancy, particularly in low-income countries. The Fe status of a breast-fed infant is strongly influenced by the body Fe content at birth, which is determined by factors that operate before birth (maternal Fe status before and during pregnancy; infant gestational age and birth weight) and at the time of delivery (the timing of umbilical cord clamping). Delaying the clamping of the umbilical cord for 2 min can increase body Fe content by approximately 33 % (75 mg), and results in greater Fe stores at 6 months of age. After birth, male gender and a rapid rate of weight gain are associated with lower Fe status. During the first half of infancy dietary Fe requirements depend on Fe stores at birth. For an exclusively-breast-fed full-term normal-birth-weight infant with delayed umbilical cord clamping, whose mother had adequate Fe status during pregnancy, the Fe provided from stores and breast milk is sufficient for ! 6 months, but before this time higher-risk infants may become Fe deficient. Fe supplementation can be beneficial for high-risk infants, but can have adverse effects on growth and morbidity of Fe-replete infants. After 6 months most breast-fed infants will require complementary foods that are rich in Fe.
引用
收藏
页码:412 / 422
页数:11
相关论文
共 62 条
[1]   Absorption of calcium, zinc, and iron from breast milk by five- to seven-month-old infants [J].
Abrams, SA ;
Wen, JP ;
Stuff, JE .
PEDIATRIC RESEARCH, 1997, 41 (03) :384-390
[2]  
BARD H, 2000, HEMATOLOGIC PROBLEMS, P365
[3]  
BAYNES RD, 2000, BIOCH PHYSL ASPECTS, P711
[4]  
BROWN MS, 1988, DEV NEONATAL HEMATOL, P249
[5]   Effect of timing of umbilical cord clamping on iron status in Mexican infants: a randomised controlled trial [J].
Chaparro, Camila M. ;
Neufeld, Lynnette M. ;
Gilberto, Tena Alavez ;
Equia-Liz Cedilla, Raul ;
Dewey, Kathryn G. .
LANCET, 2006, 367 (9527) :1997-2004
[6]  
Colomer J, 1990, Paediatr Perinat Epidemiol, V4, P196, DOI 10.1111/j.1365-3016.1990.tb00638.x
[7]  
DALLMAN PR, 1974, HEMATOLOGY INFANCY C, P108
[8]  
Dallman PR, 1993, HEMATOLOGY INFANCY C, P413
[9]  
Dallman PR, 1990, PRESENT KNOWLEDGE NU
[10]   INFLUENCE OF LACTOFERRIN ON IRON-ABSORPTION FROM HUMAN-MILK IN INFANTS [J].
DAVIDSSON, L ;
KASTENMAYER, P ;
YUEN, M ;
LONNERDAL, B ;
HURRELL, RF .
PEDIATRIC RESEARCH, 1994, 35 (01) :117-124