Progress in enantioselective catalysis assessed from an industrial point of view

被引：202

作者：

Blaser, HU ^{[1
]}

Pugin, B ^{[1
]}

Spindler, F ^{[1
]}

机构：

[1] Solvias AG, WKL 127, CH-4002 Basel, Switzerland

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2005年 / 231卷 / 1-2期

关键词：

enantioselective catalysis; industrial application; chiral ligand; catalyst performance; catalytic technology;

D O I：

10.1016/j.molcata.2004.11.025

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In this overview, the opportunities and problems associated with the industrial application of chiral catalysts (restricted to homogeneous metal complexes and modified metallic catalysts) are being analyzed in detail. In a first chapter, critical factors affecting the industrial feasibility of an enantioselective catalyst are discussed. In the following chapters, chiral catalysts with synthetic relevance are described and about 40 types of catalytic transformations are discussed in some detail and characterized regarding enantioselectivity, catalyst activity and productivity. In addition, existing selected industrial applications for pharmaceuticals, agrocheinicals and fragrances are reviewed. Finally the various transformations are assessed regarding their potential for future technical applications. (c) 2004 Elsevier B.V. All rights reserved.

引用

页码：1 / 20

页数：20

共 155 条

[1] ASYMMETRIC-SYNTHESIS BY METAL BINAP CATALYSTS
AKUTAGAWA, S
[J]. APPLIED CATALYSIS A-GENERAL, 1995, 128 (02) : 171 - 207
[2] AKUTAGAWA S, 1999, COMPREHENSIVE ASYMME, P813
[3] AKUTAGAWA S, 1999, COMPREHENSIVE ASYMME, P1461
[4] ASYMMETRIC-SYNTHESIS OF ACIDS BY THE PALLADIUM-CATALYZED HYDROCARBOXYLATION OF OLEFINS IN THE PRESENCE OF (R)-(-)-1,1'-BINAPHTHYL-2,2'-DIYL OR (S)-(+)-1,1'-BINAPHTHYL-2,2'-DIYL HYDROGEN PHOSPHATE
ALPER, H
HAMEL, N
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (07) : 2803 - 2804
[5] [Anonymous], 2000, Catalytic asymmetric synthesis
[6] [Anonymous], 1999, Comprehensive Asymmetric Catalysis
[7] [Anonymous], CATALYTIC ASYMMETRIC
[8] [Anonymous], 2002, ANGEW CHEM INT EDIT, V41, P1998
[9] [Anonymous], CATALYTIC ASYMMETRIC
[10] [Anonymous], 2000, CATALYTIC ASYMMETRIC

← 1 2 3 4 5 6 7 8 9 10 →