The rate and cost of hospital-acquired infections occurring in patients admitted to selected specialties of a district general hospital in England and the national burden imposed

被引:308
作者
Plowman, R
Graves, N
Griffin, MAS
Roberts, JA
Swan, AV
Cookson, B
Taylor, L
机构
[1] Univ London London Sch Hyg & Trop Med, Dept Publ Hlth & Policy, Hlth Serv Res Unit, London WC1E 7HT, England
[2] Cent Publ Hlth Lab, Infect Control Unit, Lab Hosp Infect, London NW9 5HT, England
[3] Publ Hlth Lab, Stat Unit, London, England
关键词
hospital-acquired infection; incidence; economic burden;
D O I
10.1053/jhin.2000.0881
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Between April 1994 and May 1995 4000 adult patients admitted to selected specialties of a district general hospital were recruited to this study. Hospital-acquired infections presenting during the inpatient stay were identified using previously validated methods of surveillance, and information on daily resource use by both infected and uninfected patients was recorded and estimates of their cost derived. Linear regression modelling techniques were used to estimate how much of the observed variation in resource use and costs could be explained by the presence of an infection. Complete in-patient data sets were obtained for 3980 patients. Of these, 309 patients (7.8%; 95% CI; 7.0, 8.6) presented with one or more hospital-acquired infections during the in-patient period. Infected patients, on average, incurred hospital costs 2.9 (regression model estimate: 2.8; 95% CI; 2.6, 3.0) times higher than uninfected patients, equivalent to an additional pound 3154 (regression model estimate pound 2917). Both the incidence and the economic impact varied with site of infection and with admission specialty. Estimates of the burden of hospital-acquired infections occurring in adult patients admitted to similar specialties at NHS hospitals in England were derived from the results of this study. An estimated 320 994 (95% CI; 288 071, 353 916) patients per annum acquire one: or more infections which present during the in-patient period, and these infections cost the hospital sector an estimated pound 930.62 million (95% CI; pound 780.26; pound 1080.97 million) per annum. The results presented represent the gross economic benefits that might accrue if these infections are prevented. Further research is required to establish the net benefits of prevention. (C) 2001 The Hospital Infection Society.
引用
收藏
页码:198 / 209
页数:12
相关论文
共 22 条
[1]  
[Anonymous], 1997, HOSP ACQUIRED INFECT
[2]   NOSOCOMIAL INFECTION - THE IRREDUCIBLE MINIMUM [J].
AYLIFFE, GAJ .
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 1986, 7 (02) :92-95
[3]  
*CHART I PUBL FIN, 1994, HEALTHC FIN MAN DAT
[4]   THE COST OF INFECTION IN SURGICAL PATIENTS - A CASE-CONTROL STUDY [J].
COELLO, R ;
GLENISTER, H ;
FERERES, J ;
BARTLETT, C ;
LEIGH, D ;
SEDGWICK, J ;
COOK, EM .
JOURNAL OF HOSPITAL INFECTION, 1993, 25 (04) :239-250
[5]  
*DEP HLTH, 1995, HOSP COMM HLTH SERV
[6]  
*DEP HLTH, 1995, HOSP EP STAT DAT
[7]  
*DH PHL, 1995, HOSP INFECT CONTR GU
[8]   The second national prevalence survey of infection in hospitals - Overview of the results [J].
Emmerson, AM ;
Enstone, JE ;
Griffin, M ;
Kelsey, MC ;
Smyth, ETM .
JOURNAL OF HOSPITAL INFECTION, 1996, 32 (03) :175-190
[9]  
FRANCIS B, 1993, GLIM4 STAT SYSTEM GE
[10]   ADVERSE-EFFECTS OF NOSOCOMIAL INFECTION [J].
FREEMAN, J ;
ROSNER, BA ;
MCGOWAN, JE .
JOURNAL OF INFECTIOUS DISEASES, 1979, 140 (05) :732-740