NreB from Achromobacter xylosoxidans 31A is a nickel-induced transporter conferring nickel resistance

被引：68

作者：

Grass, G

Fan, B

Rosen, BP

Lemke, K

Schlegel, HG

Rensing, C

机构：

[1] Univ Arizona, Dept Soil Water & Environm Sci, Tucson, AZ 85721 USA

[2] Wayne State Univ, Dept Biochem & Mol Biol, Detroit, MI 48201 USA

[3] Univ Gottingen, Inst Mikrobiol, D-37077 Gottingen, Germany

来源：

JOURNAL OF BACTERIOLOGY | 2001年 / 183卷 / 09期

关键词：

D O I：

10.1128/JB.183.9.2803-2807.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

There are two distinct nickel resistance loci on plasmid pTOM9 from Achromobacter xylosoxidans 31A, ncc and nre. Expression of the nreB gene was specifically induced by nickel and conferred nickel resistance on both A. xylosoxidans 31A and Escherichia coli. E. coli cells expressing nreB showed reduced accumulation of Ni2+, suggesting that NreB mediated nickel efflux. The histidine-rich C-terminal region of NreB mas not essential but contributed to maximal Ni2+ resistance.

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页码：2803 / 2807

页数：5

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