One micrometer resolution NMR microscopy

被引：110

作者：

Lee, SC ^{[1
]}

Kim, K

Kim, J

Lee, S ^{[1
]}

Yi, JH

Kim, SW

Ha, KS

Cheong, C

机构：

[1] Korea Adv Inst Sci & Technol, Dept Phys, Taejon 305701, South Korea

[2] Konkuk Univ, Dept Biomed Engn, Choongju 380701, South Korea

[3] Korea Basic Sci Inst, Magnet Resonance Team, Taejon 305333, South Korea

[4] Korea Basic Sci Inst, Biomol Res Team, Taejon 305333, South Korea

来源：

JOURNAL OF MAGNETIC RESONANCE | 2001年 / 150卷 / 02期

关键词：

NMR microscopy; micron resolution; diffusion analysis; high magnetic field; high gradient field;

D O I：

10.1006/jmre.2001.2319

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We obtained a magnetic resonance image of 1 mum resolution and 75 mum(3) voxel volume for a phantom filled with hydrocarbon oil within an hour at 14.1 T. For this work, a specially designed probe with a high sensitivity RF coil and gradient coils generating over 1000 G/cm was built. The optimal pulse sequence was analyzed in consideration of the bandwidth, diffusion coefficients, and T-1 and T-2 relaxations of the medium. The system was applied to the in vivo imaging of a geranium leaf stem to get the images of 2 mum resolution and 200 mum(3) voxel volume. (C) 2001 Academic Press.

引用

页码：207 / 213

页数：7

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