MUC1 in human testis and ejaculated spermatozoa and its relationship to male fertility status

被引:11
作者
Martinez-Conejero, Jose A. [1 ]
Garrido, Nicolas [2 ]
Remohi, Jose [2 ]
Pellicer, Antonio [2 ]
Simon, Carlos [1 ]
Meseguer, Marcos [2 ]
机构
[1] Fdn Inst Valenciano Infertilidad, Valencia 46015, Spain
[2] Univ Valencia, Inst Univ IVI, Valencia, Spain
关键词
D O I
10.1016/j.fertnstert.2007.06.104
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
MUC1 is a cell surface glycoprotein with a previously described antiadhesive role involved in different aspects of reproductive function. We found MUC1 expressed in male germ cell line and within the ejaculated sperm, but its presence in mature sperm does not seem to be related to male fertility. This was confirmed after analysis of results from assisted reproduction techniques with oocyte donation related with MUC1, although higher MUC1 expression is related to sperm recovery after preparation.
引用
收藏
页码:450 / 452
页数:3
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