Water-protein interactions in microcrystalline Crh measured by 1H-13C solid-state NMR spectroscopy

被引：55

作者：

Lesage, A

Böckmann, A

机构：

[1] Ecole Normale Super Lyon, Chim Lab, CNRS, ENS,UMR 5532, F-69364 Lyon, France

[2] Inst Biol & Chim Prot, CNRS, UMR 5086, F-69367 Lyon, France

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 44期

关键词：

D O I：

10.1021/ja036720y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Using solid-state NMR carbon?proton dipolar correlation spectroscopy, we observed hydrogen exchange on the millisecond time scale between water molecules and protein protons in a solid sample. These interactions are shown to be related to important structural features of the protein such as hydrogen-bonding or salt-bridge networks. Copyright © 2003 American Chemical Society.

引用

页码：13336 / 13337

页数：2

共 34 条

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