Five new antifouling sesquiterpenes from two marine sponges of the genus Axinyssa and the nudibranch Phyllidia pustulosa

被引:78
作者
Hirota, H [1 ]
Okino, T
Yoshimura, E
Fusetani, N
机构
[1] RIKEN, Japan Sci & Technol Corp, Yokoyama Cytolog Project, Wako, Saitama 3510198, Japan
[2] Utsunomiya Univ, Dept Appl Biochem, Utsunomiya, Tochigi 3218505, Japan
[3] Cent Res Inst Elect Power Ind, Abiko Res Lab, Abiko, Chiba 2701194, Japan
[4] Univ Tokyo, Grad Sch Agr & Life Sci, Bunkyo Ku, Tokyo 1138657, Japan
关键词
biologically active compounds; marine metabolites; sponges; terpenes and terpenoids;
D O I
10.1016/S0040-4020(98)00867-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Three new sesquiterpene carbonimide dichlorides have been isolated from a marine sponge of the genus Axinyssa, and a guaiane-type sesquiterpene peroxide from another Axinyssa sponge. A new isocyanosesquiterpene alcohol was obtained from the nudibranch Phyllidia pustulosa. Their structures were determined on the basis of 2D NMR data These compounds showed potent antifouling activities against larvae of the barnacle Balanus amphitrite. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:13971 / 13980
页数:10
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