New chiral synthon from the PLE catalyzed enantiomeric separation of 6-acetoxy-3-methylcyclohex-2-en-1-one

被引：26

作者：

Tanyeli, C

Demir, AS

Dikici, E

机构：

[1] Department of Chemistry, Middle East Technical University

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 08期

关键词：

D O I：

10.1016/0957-4166(96)00296-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(+/-)-6-Acetoxy-3-methylcyclohex-2-en-1-one was resolved by PLE catalyzed hydrolysis to afford (+)-6-hydroxy-3-methylcyclohex-2-en-1-one in >95% e.e. (+)-6-Hydroxy-3-methylcyclohex-2-en-1-one was transformed to its (S)-O-acetyllactyl ester derivative to determine the e.e. %. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：2399 / 2402

页数：4

共 9 条

[1]

DEMIR AS, 1991, SYNTHESIS-STUTTGART, P719

[2] OXIDATION OF ARYL ALKYL KETONES TO ALPHA-ACYLOXY, ALPHA-(CAMPHORSULFONYLOXY), OR ALPHA-HYDROXY DERIVATIVES USING MANGANESE(III) ACETATE IN COMBINATION WITH CARBOXYLIC-ACIDS OR (1S)-(+)-10-CAMPHORSULFONIC ACID [J].