Organ donation and utilization in the United States, 1997-2006

被引:94
作者
Sung, R. S. [1 ]
Galloway, J. [2 ]
Tuttle-Newhall, J. E. [3 ]
Mone, T. [4 ]
Laeng, R. [5 ]
Freise, C. E. [6 ]
Rao, P. S. [1 ]
机构
[1] Univ Michigan, Sci Registry Transplant Recipients, Ann Arbor, MI 48109 USA
[2] Arbor Res Collaborat Hlth, Sci Registry Transplant Recipients, Ann Arbor, MI USA
[3] Duke Univ Hlth Syst, Durham, NC USA
[4] OneLegacy, Los Angeles, CA USA
[5] US Hlth Resources & Serv Adm, Dept Hlth & Human Serv, Rockville, MD 20857 USA
[6] Univ Calif San Francisco, San Francisco, CA 94143 USA
关键词
deceased donors; donation after cardiac death (DCD); donation service area (DSA); expanded criteria donor (ECD); living donor; multicultural donation; Organ Donation Breakthrough Collaborative; Organ Procurement and Transplantation Network (OPTN); organ procurement organization (OPO); organs recovered per donor (ORPD); Organ Transplantation Breakthrough Collaborative; organs transplanted per donor (OTPD); Scientific Registry of Transplant Recipients (SRTR);
D O I
10.1111/j.1600-6143.2008.02171.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Deceased organ donation has increased rapidly since 2002, coinciding with implementation of the Organ Donation Breakthrough Collaborative. The increase in donors has resulted in a corresponding increase in the numbers of kidney, liver, lung and intestinal transplants. While transplants for most organs have increased, discard and nonrecovery rates have not improved or have increased, resulting in a decrease in organs recovered per donor (ORPD) and organs transplanted per donor (OTPD). Thus, the expansion of the consent and recovery of incremental donors has frequently outpaced utilization. Meaningful increases in multicultural donation have been achieved, but donations continue to be lower than actual rates of transplantation and waiting list registrations for these groups. To counteract the decline in living donation, mechanisms such as paired donation and enhanced incentives to organ donation are being developed. Current efforts of the collaborative have focused on differentiating ORPD and OTPD targets by donor type (standard and expanded criteria donors and donors after cardiac death), utilization of the OPTN regional structure and enlisting centers to increase transplants to match increasing organ availability.
引用
收藏
页码:922 / 934
页数:13
相关论文
共 11 条
[1]
The economic impact of the utilization of liver allografts with high donor risk index [J].
Axelrod, D. A. ;
Schnitzler, M. ;
Salvalaggio, P. R. ;
Swindle, J. ;
Abecassis, M. M. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2007, 7 (04) :990-997
[2]
A primer on leading the improvement of systems [J].
Berwick, DM .
BRITISH MEDICAL JOURNAL, 1996, 312 (7031) :619-622
[3]
Delmonico F.L., 2004, AM J TRANSPLANT
[4]
*DON LIF AM DON DE, 2007, DON LIF AM 2007 SPR
[5]
Outcome of kidney transplantation using expanded criteria donors and donation after cardiac death kidneys: Realities and costs [J].
Saidi, R. F. ;
Elias, N. ;
Kawai, T. ;
Hertl, M. ;
Farrell, M.-L. ;
Goes, N. ;
Wong, W. ;
Hartono, C. ;
Fishman, J. A. ;
Kotton, C. N. ;
Tolkoff-Rubin, N. ;
Delmonico, F. L. ;
Cosimi, A. B. ;
Ko, D. S. C. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2007, 7 (12) :2769-2774
[6]
Increasing the opportunity of live kidney donation by matching for two- and three-way exchanges [J].
Saidman, SL ;
Roth, AE ;
Sönmez, T ;
Ünver, MU ;
Delmonico, FL .
TRANSPLANTATION, 2006, 81 (05) :773-782
[7]
Estimating the number of potential organ donors in the United States. [J].
Sheehy, E ;
Conrad, SL ;
Brigham, LE ;
Luskin, R ;
Weber, P ;
Eakin, M ;
Schkade, L ;
Hunsicker, L .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (07) :667-674
[8]
STEGALL MD, 2007, AM J TRANSPLANT, V83, P1156
[9]
*US BUR CENS, 2008, ANN EST POP SEX RAC
[10]
Incompatible kidney donor candidates' willingness to participate in donor-exchange and non-directed donation [J].
Waterman, A. D. ;
Schenk, E. A. ;
Barrett, A. C. ;
Waterman, B. M. ;
Rodrigue, J. R. ;
Woodle, E. S. ;
Shenoy, S. ;
Jendrisak, M. ;
Schnitzler, M. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (07) :1631-1638