Avalanches in the lung: A statistical mechanical model

被引:40
作者
Barabasi, AL
Buldyrev, SV
Stanley, HE
Suki, B
机构
[1] BOSTON UNIV, DEPT PHYS, BOSTON, MA 02215 USA
[2] UNIV NOTRE DAME, DEPT PHYS, NOTRE DAME, IN 46556 USA
[3] BOSTON UNIV, DEPT BIOMED ENGN, RESP RES LAB, BOSTON, MA 02215 USA
关键词
D O I
10.1103/PhysRevLett.76.2192
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We study a statistical mechanical model for the dynamics of lung inflation which incorporates recent experimental observations on the opening of individual airways by a cascade or avalanche mechanism. Using an exact mapping of the avalanche problem onto percolation on a Cayley tree, we analytically derive the exponents describing the size distribution of the first avalanches and test the analytical solution by numerical simulations. We find that the treelike structure of the airways, together with the simplest assumptions concerning opening threshold pressures of each airway, is sufficient to explain the existence of power-law distributions observed experimentally.
引用
收藏
页码:2192 / 2195
页数:4
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