Sonographic assessment of endometrial pattern and thickness in patients treated with human menopausal gonadotropins

被引:20
作者
Bohrer, MK
Hock, DL
Rhoads, GG
Kemmann, E
机构
[1] UNIV MED & DENT NEW JERSEY,ROBERT WOOD JOHNSON MED SCH,DEPT OBSTET & GYNECOL,NEW BRUNSWICK,NJ
[2] UNIV MED & DENT NEW JERSEY,ROBERT WOOD JOHNSON MED SCH,NEW BRUNSWICK,NJ
关键词
endometrium; transvaginal sonography; endometrial pattern; endometrial thickness;
D O I
10.1016/S0015-0282(16)58447-7
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To analyze sonographically the endometrium in patients undergoing controlled ovarian stimulation with menotropins in order to determine the significance of endometrial pattern and thickness on pregnancy rate. Design: This is a prospective, nonrandomized study comparing pregnancy rates in patients with hyperechoic homogeneous patterns with those in patients with isoechoic or hypoechoic trilaminar patterns. Setting: Tertiary infertility center. Patients: All patients receiving menotropin therapy at a tertiary infertility center. Interventions: All patients received individualized dosing of hMG starting on cycle day 3. Transvaginal sonography was performed 15 hours before hCG administration and the endometrium was assessed. Main Outcome Measure: Occurrence of pregnancy as determined by serially rising beta-hCG titers and sonographic confirmation. Results: During the study period, 175 patients were evaluated. Thirty-four (19%) patients had a homogeneous endometrium, whereas 141 (81%) patients had a trilaminar pattern. There was 1 pregnancy(2.9%) among women with a homogeneous endometrial pattern and 33 pregnancies (23%) among those with a trilaminar pattern. No significant differences were found in mean E(2) level, follicle numbers, parity, and diagnosis between the two groups. Conclusion: In patients receiving menotropins, a homogeneous pattern is a bad prognostic sign, regardless of endometrial thickness.
引用
收藏
页码:244 / 247
页数:4
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