Synthesis of ammonium substituted β-cyclodextrins for enantioseparation of anionic analytes

被引：35

作者：

Muderawan, IW

Ong, TT

Tang, W

Young, DJ ^{[1
]}

Ching, CB

Ng, SC

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

[2] Inst Chem & Engn Sci Ltd, Singapore 627833, Singapore

[3] Nanyang Technol Univ, Div Chem & Biomol Engn, Singapore 639798, Singapore

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 10期

关键词：

cationic cyclodextrins; enantiomeric resolution;

D O I：

10.1016/j.tetlet.2005.01.059

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New ammonium functionalized cyclodextrins can be prepared in excellent yields by displacement of 6-tosyl-beta-cyclodextrin with alkylimidazoles, pyridine or alkylamines and achieve excellent enantioseparation of dansyl amino acids presumably due to electrostatic interactions between the cationic host and anionic guest. (C) 2005 Published by Elsevier Ltd.

引用

收藏

页码：1747 / 1749

页数：3

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