Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope

被引：131

作者：

Merino, David ^{[1
]}

Duncan, Jacque L. ^{[1
]}

Tiruveedhula, Pavan ^{[2
]}

Roorda, Austin ^{[2
]}

机构：

[1] Univ Calif San Francisco, Dept Ophthalmol, San Francisco, CA 94143 USA

[2] Univ Calif Berkeley, Sch Optometry, Berkeley, CA 94720 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2011年 / 2卷 / 08期

基金：

美国国家卫生研究院;

关键词：

OCCULT OUTER RETINOPATHY; HIGH-RESOLUTION; COHERENCE TOMOGRAPHY; DENSITY; SEGMENT; IMAGES; LAYER;

D O I：

10.1364/BOE.2.002189

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

We demonstrate the capability of a new generation adaptive optics scanning laser ophthalmoscope (AOSLO) to resolve cones and rods in normal subjects, and confirm our findings by comparing cone and rod spacing with published histology measurements. Cone and rod spacing measurements are also performed on AOSLO images from two different diseased eyes, one affected by achromatopsia and the other by acute zonal occult outer retinopathy (AZOOR). The potential of AOSLO technology in the study of these and other retinal diseases is illustrated. (C) 2011 Optical Society of America

引用

页码：2189 / 2201

页数：13

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