The histopathological effects of Thiodan® on the liver and gut of mosquitofish, Gambusia affinis

被引：40

作者：

Cengiz, EI ^{[1
]}

Ünlü, E ^{[1
]}

Balci, K ^{[1
]}

机构：

[1] Dicle Univ, Fac Sci & Art, Dept Biol, TR-21280 Diyarbakir, Turkey

来源：

JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES | 2001年 / 36卷 / 01期

关键词：

pesticides; Gambusia affinis; histopathology; gut; liver;

D O I：

10.1081/PFC-100000918

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Thiodan (R) (33.7% endosulfan), a polychlorinated cyclodiene insecticide, was evaluated for its histopathological effects on mosquitofish, Gambusia affinis, by light microscopy. Fish were exposed to doses of 0.00 (control), 1.00, 2.50, and 5.00 mug/L on days 7, 14, 21, and 30. No histopathological effects were apparent at control group. The histopathological alterations were characterized as oedema, degeneration, accumulation of lymphocytes in the lamina propria, disintegration of villuses, pycnotic state of nuclei, and necrosis in gut; degeneration, hypertrophy, sinusoids enlargement, hemorrhage, pycnosis position of nuclei, vacuolization of cell cytoplasm, infiltration of mononuclear lymphocyte, and congestion in liver. These alterations were time- and dose-dependent.

引用

页码：75 / 85

页数：11

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