Use of solid supported nucleophiles and electrophiles for the purification of non-peptide small molecule libraries

被引：228

作者：

Kaldor, SW

Siegel, MG

Fritz, JE

Dressman, BA

Hahn, PJ

机构：

[1] Lilly Research Laboratories, Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 40期

关键词：

D O I：

10.1016/0040-4039(96)01636-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Solid supported nucleophiles and electrophiles are employed to expedite the work-up and purification of a variety of amine alkylations and acylations. These solid suported scavengers are particularly advantageous for the construction of non-peptide libraries in a parallel array format. Copyright (C) 1996 Elsevier Science Ltd

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收藏

页码：7193 / 7196

页数：4

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