Melanopsin and other novel mammalian opsins

被引：59

作者：

Kumbalasiri, T

Provencio, I

机构：

[1] Univ Virginia, Dept Biol, Charlottesville, VA 22903 USA

[2] Uniformed Serv Univ Hlth Sci, Grad Program Neurosci, Bethesda, MD 20814 USA

来源：

EXPERIMENTAL EYE RESEARCH | 2005年 / 81卷 / 04期

关键词：

chromophore; circadian; opsin; photoisomerase; photopigment; retinaldehyde;

D O I：

10.1016/j.exer.2005.05.004

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Within the past decade, several non-canonical opsins have been identified in mammals. These include RGR, peropsin, melanopsin, encephalopsin, and neuropsin. Although all are expressed in the eye, it is likely that they serve to mediate non-visual effects of light on physiology. Some of these opsins, however, may play an indirect role in vision by generating appropriate retinoid chromophores for the rod and cone visual pigments or by regulating the sensitivity of the visual system. Here, we survey the current state of knowledge regarding these opsins. (c) 2005 Elsevier Ltd. All rights reserved.

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收藏

页码：368 / 375

页数：8

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