Ester-type cephalotaxus alkaloids from Cephalotaxus harringtonia var drupacea

被引：28

作者：

Takano, I ^{[1
]}

Yasuda, I ^{[1
]}

Nishijima, M ^{[1
]}

Yanagi, Y ^{[1
]}

Takeya, K ^{[1
]}

Itokawa, H ^{[1
]}

机构：

[1] TOKYO UNIV PHARM & LIFE SCI,HACHIOJI,TOKYO 19203,JAPAN

来源：

PHYTOCHEMISTRY | 1997年 / 44卷 / 04期

关键词：

Cephalotaxus harringtonia var drupacea; Cephalotaxaceae; alkaloids; neoharringtonine; homoneoharringtonine; 3'S-hydroxyneoharringtonine; antileukaemic activities;

D O I：

10.1016/S0031-9422(96)00574-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S-hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was evaluated using P-388 leukaemia cells. Copyright (C) 1997 Elsevier Science Ltd.

引用

页码：735 / 738

页数：4

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