Validation of Self-swab for Virologic Confirmation of Influenza Virus Infections in a Community Setting

被引：28

作者：

Ip, Dennis K. M. ^{[1
]}

Schutten, Martin ^{[3
]}

Fang, Vicky J.

Fung, Rita O. P.

Dutkowski, Regina T. ^{[4
]}

Chan, Kwok-Hung ^{[2
]}

Leung, Gabriel M.

Peiris, J. S. Malik ^{[2
]}

Cowling, Benjamin J.

机构：

[1] Univ Hong Kong, Sch Publ Hlth, Li Ka Shing Fac Med, Units 624 7, Pokfulam, Hong Kong, Peoples R China

[2] Univ Hong Kong, Dept Microbiol, Pokfulam, Hong Kong, Peoples R China

[3] Erasmus MC, Rotterdam, Netherlands

[4] Hoffmann La Roche, Nutley, NJ USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2012年 / 205卷 / 04期

基金：

美国国家卫生研究院;

关键词：

RESPIRATORY VIRUSES; FLOCKED SWABS; CHILDREN; METAPNEUMOVIRUS; EPIDEMIOLOGY; HOUSEHOLDS; DISEASE;

D O I：

10.1093/infdis/jir803

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Few studies have investigated the validity of self-collected nose and throat swabs for influenza confirmation in community settings. We followed outpatients with confirmed influenza with sequential measurement of viral loads and applied log-linear regression models to the viral shedding patterns. Among 176 outpatients with confirmed influenza, the detection of virus and quantitative viral loads obtained from self-swabs was consistent with statistical predictions based on earlier and later measurements, suggesting that self-collected nose and throat swabs can be a valid alternative for virologic confirmation of influenza A or B infection in a community setting.

引用

页码：631 / 634

页数：4

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