The first Irish genome and ways of improving sequence accuracy

被引：4

作者：

Ju, Young Seok ^{[1
]}

Yoo, Yun Joo ^{[1
,2
]}

Kim, Jong-Il ^{[1
,3
]}

Seo, Jeong-Sun ^{[1
,3
]}

机构：

[1] Seoul Natl Univ, Genom Med Inst, Med Res Ctr, Seoul 110799, South Korea

[2] Seoul Natl Univ, Dept Math Educ, Seoul 151742, South Korea

[3] Seoul Natl Univ Coll Med, Dept Biochem & Mol Biol, Seoul 110799, South Korea

来源：

GENOME BIOLOGY | 2010年 / 11卷 / 09期

关键词：

Sequencing Coverage; Personal Genome; Individual Genome; Heterozygous Variant; Haplotype Inference;

D O I：

10.1186/gb-2010-11-9-132

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Whole-genome sequencing of an Irish person reveals hundreds of thousands of novel genomic variants. Imputation using previous known information improves the accuracy of low-read-depth sequencing.

引用

页数：4

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