Near infrared spectroscopy in fermentation and quality control for amino acid production

被引：13

作者：

Schmidt, S

Kircher, M

Kasala, J

Locaj, J

机构：

[1] Forschungszentrum Julich, D-52425 Julich, Germany

[2] Degussa AG, D-63457 Hanau, Germany

[3] Fermas Spol SRO, SK-97613 Slovenska Lupca, Slovakia

来源：

BIOPROCESS ENGINEERING | 1998年 / 19卷 / 01期

关键词：

Spectroscopy; Ammonia; Fermentation; Optical Density; Quality Control;

D O I：

10.1007/s004490050484

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The application of near infrared spectroscopy (NIRS) for in-process and quality control of fermentative production of L-lysine and L-threonine in industrial scale is presented. NIRS is a helpful tool for predicting optical density, ammonia, L-threonine and L-lysine in fermentation broth. For dry and solid product, Biolys(R)60, NIRS is suitable to give a quick estimation of L-lysine and water content.

引用

页码：67 / 70

页数：4

共 7 条

[1] BRIMMER PJ, 1993, CAN J APPL SPECTROSC, V38, P155
[2] Simultaneous measurements of glucose, glutamine, ammonia, lactate, and glutamate in aqueous solutions by near-infrared spectroscopy
Chung, H
Arnold, MA
Rhiel, M
Murhammer, DW
[J]. APPLIED SPECTROSCOPY, 1996, 50 (02) : 270 - 276
[3] Near-infrared spectroscopic determination of acetate, ammonium, biomass, and glycerol in an industrial Escherichia coli fermentation
Hall, JW
McNeil, B
Rollins, MJ
Draper, I
Thompson, BG
Macaloney, G
[J]. APPLIED SPECTROSCOPY, 1996, 50 (01) : 102 - 108
[4] HAMMOND SV, 1992, CONF P ACS, P325
[5] TONKS DB, 1968, Z ANAL CHEM FRESENIU, V243, P760
[6] A NEAR-INFRARED SPECTROSCOPY TECHNIQUE FOR THE CONTROL OF FERMENTATION PROCESSES - AN APPLICATION TO LACTIC-ACID FERMENTATION
VACCARI, G
DOSI, E
CAMPI, AL
GONZALEZVARA, A
MATTEUZZI, D
MANTOVANI, G
[J]. BIOTECHNOLOGY AND BIOENGINEERING, 1994, 43 (10) : 913 - 917
[7] VANDERVLIES C, 1996, EUROPEAN PHARM REV, V2, P49

← 1 →