Are the stainless steel electrodes inert?

被引:27
作者
Tomov, T [1 ]
Tsoneva, I [1 ]
机构
[1] Bulgarian Acad Sci, Inst Biophys, BU-1113 Sofia, Bulgaria
来源
BIOELECTROCHEMISTRY | 2000年 / 51卷 / 02期
基金
美国国家科学基金会;
关键词
stainless steel electrodes; electroporation; electrochemotherapy; bleomycin;
D O I
10.1016/S0302-4598(00)00069-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The electrodes used for electroporation, electrofusion, and electrotransfection, as well as in electrochemotherapy should not interact with the object and release electrolysis products. We studied how far the stainless steel electrodes fulfil these requirements. The results showed that in the case of the exponential electric pulses with amplitude of 3 kV cm(-1) and time constant of 0.5 ms, the stainless steel electrodes released ferrous ions to a concentration of several micromoles per liter. We determined experimentally the dependence of the amount of the released ferrous ions on the pulse parameters and on the ionic strength of the medium. It was shown that the released ferrous ions should not be ignored. They could be of importance for the bleomycin electrochemotherapy. (C) 2000 Elsevier Science S.A. All rights reserved.
引用
收藏
页码:207 / 209
页数:3
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