Transient benefit only from increasing the imatinib dose in CML patients who do not achieve complete cytogenetic remissions on conventional doses

被引:59
作者
Marin, D [1 ]
Goldman, JM [1 ]
Olavarria, E [1 ]
Apperley, JF [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Dept Haematol, London W12 0NN, England
关键词
D O I
10.1182/blood-2003-06-2042
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2702 / 2703
页数:2
相关论文
共 5 条
[1]   Management decisions in chronic myeloid leukemia [J].
Goldman, JA ;
Marin, D .
SEMINARS IN HEMATOLOGY, 2003, 40 (01) :97-103
[2]   Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. [J].
Kantarjian, H ;
Sawyers, C ;
Hochhaus, A ;
Guilhot, F ;
Schiffer, C ;
Gambacorti-Passerini, C ;
Niederwieser, D ;
Resta, D ;
Capdeville, R ;
Zoellner, U ;
Talpaz, M ;
Druker, B .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (09) :645-652
[3]   Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia [J].
Kantarjian, HM ;
Talpaz, M ;
O'Brien, S ;
Giles, F ;
Garcia-Manero, G ;
Faderl, S ;
Thomas, D ;
Shan, JQ ;
Rios, MB ;
Cortes, J .
BLOOD, 2003, 101 (02) :473-475
[4]   Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia [J].
O'Brien, SG ;
Guilhot, F ;
Larson, RA ;
Gathmann, I ;
Baccarani, M ;
Cervantes, F ;
Cornelissen, JJ ;
Fischer, T ;
Hochhaus, A ;
Hughes, T ;
Lechner, K ;
Nielsen, JL ;
Rousselot, P ;
Reiffers, J ;
Saglio, G ;
Shepherd, J ;
Simonsson, B ;
Gratwohl, A ;
Goldman, JM ;
Kantarjian, H ;
Taylor, K ;
Verhoef, G ;
Bolton, AE ;
Capdeville, R ;
Druker, BJ ;
Durrant, S ;
Schwarer, A ;
Joske, D ;
Seymour, J ;
Grigg, A ;
Ma, D ;
Arthur, C ;
Bradstock, K ;
Joshua, D ;
Louwagie, A ;
Martiat, P ;
Straetmans, N ;
Bosly, A ;
Shustik, C ;
Lipton, J ;
Forrest, D ;
Walker, I ;
Roy, DC ;
Rubinger, M ;
Bence-Bruckler, I ;
Kovacs, M ;
Turner, AR ;
Birgens, H ;
Bjerrum, O ;
Facon, T .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (11) :994-1004
[5]  
Zonder JA, 2003, CLIN CANCER RES, V9, P2092