Metazoan replication-dependent histone mRNAs: a distinct set of RNA polymerase II transcripts

被引：111

作者：

Marzluff, WF ^{[1
]}

机构：

[1] Univ N Carolina, Dept Biochem & Biophys, Program Mol Biol & Biotechnol, Chapel Hill, NC 27599 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2005年 / 17卷 / 03期

关键词：

D O I：

10.1016/j.ceb.2005.04.010

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Metazoan replication-dependent histone mRNAs are the only eukaryotic mRNAs that lack polyA tails. The genes for the five histone proteins have remained physically linked during evolution. Expression of histone mRNAs and histone proteins requires a unique set of factors, and may be coordinated by association of the histone genes with Cajal bodies. Recently several novel factors, including components of the U7 snRNP, as well as proteins involved in regulation of histone gene expression, have been described.

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页码：274 / 280

页数：7

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