Organic synthesis using polymer-supported reagents, catalysts and scavengers in simple laboratory flow systems

被引：76

作者：

Hodge, P ^{[1
]}

机构：

[1] Univ Manchester, Dept Chem, Manchester M13 9PL, Lancs, England

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2003年 / 7卷 / 03期

关键词：

D O I：

10.1016/S1367-5931(03)00052-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The use of appropriate combinations of polymer-supported reagents, catalysts and/or scavengers is a powerful approach, both for the synthesis of single organic compounds and for parallel syntheses. A further stage of development is the use of such reactants in flow systems. So far, it has been shown that a variety of flow formats afford excellent chemical yields and, where relevant, excellent enantiomeric excesses. The supports have a longer lifetime than in batch systems. 'Flow cascades' promise to be important in future.

引用

页码：362 / 373

页数：12

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