Facile inversion of configuration of N-Boc-β-aminoalcohols via SN2 cyclization to oxazolidinones

被引：49

作者：

Benedetti, F ^{[1
]}

Norbedo, S ^{[1
]}

机构：

[1] Univ Trieste, Dept Chem Sci, I-34127 Trieste, Italy

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 51期

关键词：

amino alcohols; oxazolidinones; inversion reactions; cyclization;

D O I：

10.1016/S0040-4039(00)01753-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxazolidinones are obtained by the cyclization of mesylates derived from N-Boc-beta -aminoalcohols. Hydrolysis of the N-Boc-oxazolidinones regenerates the protected aminoalcohols with inverted configuration at the hydroxy group. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：10071 / 10074

页数：4

共 18 条

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