Efficacy, pharmacology, and adverse effects of antiepileptic drugs

被引:33
作者
Holland, KD [1 ]
机构
[1] Cleveland Clin Fdn, Sect Pediat Epilepsy, Cleveland, OH 44195 USA
关键词
D O I
10.1016/S0733-8619(05)70021-9
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This article discusses the factors involved in the appropriate selection of anticonvulsant medications. The clinical use of commonly used traditional antiepileptic drugs and the newly marketed antiepileptic drugs is discussed. This includes the specific indications for use, adverse effects, and dosing of each drug. Drug interactions, mechanisms of action, and pharmacological properties of each drug is also reviewed.
引用
收藏
页码:313 / +
页数:34
相关论文
共 126 条
[1]  
[Anonymous], 1994, Epilepsy Res, V18, P67
[2]   VALPROATE-ASSOCIATED PANCREATITIS [J].
ASCONAPE, JJ ;
PENRY, JK ;
DREIFUSS, FE ;
RIELA, A ;
MIRZA, W .
EPILEPSIA, 1993, 34 (01) :177-183
[3]   Pharmacokinetics of fosphenytoin in patients with hepatic or renal disease [J].
Aweeka, FT ;
Gottwald, MD ;
Gambertoglio, JG ;
Wright, TL ;
Boyer, TD ;
Pollock, AS ;
Eldon, MA ;
Kugler, AR ;
Alldredge, BK .
EPILEPSIA, 1999, 40 (06) :777-782
[4]  
BANFIELD CR, 1995, ANTIEPILEPTIC DRUGS
[5]   OXCARBAZEPINE - PHARMACOKINETIC INTERACTIONS AND THEIR CLINICAL RELEVANCE [J].
BARUZZI, A ;
ALBANI, F ;
RIVA, R .
EPILEPSIA, 1994, 35 :S14-S19
[6]   CROSS-REACTIVE SKIN ERUPTION WITH BOTH CARBAMAZEPINE AND OXCARBAZEPINE [J].
BERAN, RG .
EPILEPSIA, 1993, 34 (01) :163-165
[7]   COMPARATIVE PHARMACOKINETICS OF THE NEWER ANTIEPILEPTIC DRUGS [J].
BIALER, M .
CLINICAL PHARMACOKINETICS, 1993, 24 (06) :441-452
[8]  
BIALER M, 1995, ANTIEPILEPTIC DRUGS
[9]   A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy [J].
Bill, PA ;
Vigonius, U ;
Pohlmann, H ;
Guerreiro, CAM ;
Kochen, S ;
Saffer, D ;
Moore, A .
EPILEPSY RESEARCH, 1997, 27 (03) :195-204
[10]   Drug interaction profile of topiramate [J].
Bourgeois, BFD .
EPILEPSIA, 1996, 37 :S14-S17