A short procedure for synthesis of 4-ethynyl-2,2,6,6-tetramethyl-3,4-dehydro-piperidine-1-oxyl nitroxide

被引：17

作者：

Gannett, PM ^{[1
]}

Darian, E ^{[1
]}

Powell, JH ^{[1
]}

Johnson, EM ^{[1
]}

机构：

[1] W Virginia Univ, Sch Pharm, Morgantown, WV 26506 USA

来源：

SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 14期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1081/SCC-100104464

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The spin-probe labeling technique has been applied to DNA and offers the possibility of studying antisense agents in cells. Simpler syntheses of spin-probes for incorporation into DNA would facilitate this. Here, we describe the synthesis of a new spin probe that requires half the number of steps of related 5 ring nitroxide.

引用

页码：2137 / 2141

页数：5

共 8 条

[1]

Martin RE, 1998, ANGEW CHEM INT EDIT, V37, P2834, DOI 10.1002/(SICI)1521-3773(19981102)37:20<2833::AID-ANIE2833>3.0.CO

[2]

2-7

[3] TRIPLEX DNA FINALLY COMES OF AGE [J].