A three-component coupling protocol for the synthesis of substituted hexahydropyrrolo[3,2-c]quinolines

被引：120

作者：

Batey, RA ^{[1
]}

Simoncic, PD ^{[1
]}

Lin, D ^{[1
]}

Smyj, RP ^{[1
]}

Lough, AJ ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 07期

关键词：

D O I：

10.1039/a809614g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

One pot reaction of anilines, benzaldehydes and 2-pyrrolines under lanthanide triflate catalysis affords substituted hexahydropyrrolo[3,2-c]quinolines in good to excellent yields.

引用

页码：651 / 652

页数：2

共 25 条

[1] [Anonymous], 1991, Comprehensive Organic Synthesis
[2] Multiple-component condensation strategies for combinatorial library synthesis
Armstrong, RW
Combs, AP
Tempest, PA
Brown, SD
Keating, TA
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1996, 29 (03) : 123 - 131
[3] REVERSIBLE INHIBITORS OF THE GASTRIC (H+/K+)-ATPASE .1. 1-ARYL-4-METHYLPYRROLO[3,2-C]QUINOLINES AS CONFORMATIONALLY RESTRAINED ANALOGS OF 4-(ARYLAMINO)QUINOLINES
BROWN, TH
IFE, RJ
KEELING, DJ
LAING, SM
LEACH, CA
PARSONS, ME
PRICE, CA
REAVILL, DR
WIGGALL, KJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (02) : 527 - 533
[4] Gurjar MK, 1997, HETEROCYCLES, V45, P231
[5] Bradykinin receptors
Hall, JM
[J]. GENERAL PHARMACOLOGY, 1997, 28 (01): : 1 - 6
[6] A synthesis of the tricyclic pyrroloquinoline core of martinelline
Ho, TCT
Jones, K
[J]. TETRAHEDRON, 1997, 53 (24) : 8287 - 8294
[7] Imamoto T., 1994, LANTHANIDES ORGANIC
[8] SYNTHESIS OF 4-HETEROCYCLYL-HEXAHYDRO-8-METHOXYFURO[3,2-C]QUINOLINES BY LEWIS ACID-CATALYZED [4+2]CYCLOADDITION REACTION
KAMETANI, T
FURUYAMA, H
FUKUOKA, Y
TAKEDA, H
SUZUKI, Y
HONDA, T
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1986, 23 (01) : 185 - 187
[9] SYNTHESIS OF QUINOLINE DERIVATIVES BY [4+2]CYCLOADDITION REACTION
KAMETANI, T
TAKEDA, H
SUZUKI, Y
HONDA, T
[J]. SYNTHETIC COMMUNICATIONS, 1985, 15 (06) : 499 - 505
[10] Recent progress in the synthesis of 1,2,3,4-tetrahydroquinolines
Katritzky, AR
Rachwal, S
Rachwal, B
[J]. TETRAHEDRON, 1996, 52 (48) : 15031 - 15070

← 1 2 3 →