Oxaliplatin-induced immune hemolytic anemia: a case report and review of the literature

被引:7
作者
Cobo, Francesc [1 ]
De Celis, Guillern
Pereira, Arturo
Latorre, Xavier
Pujadas, Jaume
Albiol, Santiago
机构
[1] Hosp Ntra Sra, Oncohematol Unit, De Meritxell, Escaldes Engord, Andorra
[2] Hosp Ntra Sra, Dept Internal Med, De Meritxell, Escaldes Engord, Andorra
[3] Hosp Clin Barcelona, Immunohematol Unit, Dept Hemotherapy & Hemostasis, Barcelona, Spain
关键词
chemotherapy; colorectal cancer; immune cytopenia;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
We report a 59-year-old woman diagnosed with metastasic colorectal cancer who developed immune hemolytic anemia during FOLFOX chemotherapy (oxaliplatin/leucovorin/5-fluorouracil). lmmunohematologic studies demonstrated that immune hemolysis was oxaliplatin-mediated. On the basis of this case and in a review of the literature in which 13 cases of previously reported oxaliplatin-induced immune cytopenia have been identified, we suggest some clinical clues regarding the use of oxaliplatin in cancer patients.
引用
收藏
页码:973 / 976
页数:4
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