Unmanageable motivation in addiction: A pathology in prefrontal-accumbens glutamate transmission

被引:460
作者
Kalivas, PW [1 ]
Volkow, N
Seamans, J
机构
[1] Med Univ S Carolina, Dept Neurosci, Charleston, SC 29465 USA
[2] NIDA, Bethesda, MD 20892 USA
关键词
D O I
10.1016/j.neuron.2005.02.005
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:647 / 650
页数:4
相关论文
共 23 条
[1]   Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse [J].
Baker, DA ;
McFarland, K ;
Lake, RW ;
Shen, H ;
Tang, XC ;
Toda, S ;
Kalivas, PW .
NATURE NEUROSCIENCE, 2003, 6 (07) :743-749
[2]   Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: Comparison between cocaine and a potent conventional reinforcer [J].
Baptista, MAS ;
Martin-Fardon, R ;
Weiss, F .
JOURNAL OF NEUROSCIENCE, 2004, 24 (20) :4723-4727
[3]   Activator of G protein signaling 3: A gatekeeper of cocaine sensitization and drug seeking [J].
Bowers, MS ;
McFarland, K ;
Lake, RW ;
Peterson, YK ;
Lapish, CC ;
Gregory, ML ;
Lanier, SM ;
Kalivas, PW .
NEURON, 2004, 42 (02) :269-281
[4]   A role for the prefrontal cortex in stress- and cocaine-induced reinstatement of cocaine seeking in rats [J].
Capriles, N ;
Rodaros, D ;
Sorge, RE ;
Stewart, J .
PSYCHOPHARMACOLOGY, 2003, 168 (1-2) :66-74
[5]   Ethanol and brain plasticity: receptors and molecular networks of the postsynaptic density as targets of ethanol [J].
Chandler, LJ .
PHARMACOLOGY & THERAPEUTICS, 2003, 99 (03) :311-326
[6]   Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction [J].
Cornish, JL ;
Kalivas, PW .
JOURNAL OF NEUROSCIENCE, 2000, 20 (15) :art. no.-RC89
[7]   Dissociable effects of antagonism of NMDA and AMPA/KA receptors in the nucleus accumbens core and shell on cocaine-seeking behavior [J].
Di Ciano, P ;
Everitt, BJ .
NEUROPSYCHOPHARMACOLOGY, 2001, 25 (03) :341-360
[8]   Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus [J].
Dietrich, D ;
Kral, T ;
Clusmann, H ;
Friedl, M ;
Schramm, J .
NEUROPHARMACOLOGY, 2002, 42 (03) :297-305
[9]   Cue-induced cocaine craving: Neuroanatomical specificity for drug users and drug stimuli [J].
Garavan, H ;
Pankiewicz, J ;
Bloom, A ;
Cho, JK ;
Sperry, L ;
Ross, TJ ;
Salmeron, BJ ;
Risinger, R ;
Kelley, D ;
Stein, EA .
AMERICAN JOURNAL OF PSYCHIATRY, 2000, 157 (11) :1789-1798
[10]   Drug addiction and its underlying neurobiological basis: Neuroimaging evidence for the involvement of the frontal cortex [J].
Goldstein, RZ ;
Volkow, ND .
AMERICAN JOURNAL OF PSYCHIATRY, 2002, 159 (10) :1642-1652