Isolation of symlandine from the roots of common comfrey (Symphytum officinale) using countercurrent chromatography

被引：28

作者：

Kim, NC ^{[1
]}

Oberlies, NH ^{[1
]}

Brine, DR ^{[1
]}

Handy, RW ^{[1
]}

Wani, MC ^{[1
]}

Wall, ME ^{[1
]}

机构：

[1] Res Triangle Inst, Res Triangle Pk, NC 27709 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 02期

关键词：

D O I：

10.1021/np0004653

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three pyrrolizidine alkaloids, symlandine, symphytine, and echimidine (1-3), were isolated from the roots of Symphytum officinale using a one-step countercurrent chromatography procedure. The structures of 1-3 were confirmed by several spectroscopic techniques including 2D NMR, methods. This is the first description of the separation of symlandine (1) from its stereoisomer, symphytine (2).

引用

页码：251 / 253

页数：3

共 16 条

[1]

Awang D. V. C., 1993, Journal of Herbs, Spices & Medicinal Plants, V2, P21, DOI 10.1300/J044v02n01_04

[2] DETERMINATION OF PYRROLIZIDINE ALKALOIDS IN COMMERCIAL COMFREY PRODUCTS (SYMPTHYTUM SP) [J].