Copper-catalyzed oxidative cyclization of α-hydroxyketones with o-phenylenediamines leading to quinoxalines

被引：71

作者：

Cho, Chan Sik ^{[1
]}

Oh, Sung Gi

机构：

[1] Kyungpook Natl Univ, Res Inst Ind Technol, Taegu 702701, South Korea

[2] Kyungpook Natl Univ, Dept Appl Chem, Taegu 702701, South Korea

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2007年 / 276卷 / 1-2期

关键词：

copper catalyst; alpha-hydroxyketones; oxidative cyclization; o-phenylenediarnines; quinoxalines;

D O I：

10.1016/j.molcata.2007.07.014

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

alpha-Hydroxyketones are oxidatively cyclized with o-phenylenediamines in toluene at 120 degrees C under an atmosphere of air in the presence of a catalytic amount of a copper catalyst along with powdered 4A molecular sieves to afford the corresponding quinoxalines in high yields. The reaction is applicable to a wide range of alpha-hydroxyketones which have various aryl and alkyl groups attached to carbonyl carbon. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：205 / 210

页数：6

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