Mediator complexes and transcription

被引:204
作者
Rachez, C [1 ]
Freedman, LP [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Cell Biol Program, New York, NY 10021 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0955-0674(00)00209-X
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Over the past decade, various components of the transcription machinery have been identified as potential targets for activators. Recently, metazoan versions of yeast Mediator have been isolated and found to act as key coactivators to many transcription factors. Recent work has defined the composition, function and biology of metazoan mediator complexes, which has led us to propose a new nomenclature for the variously named versions of the mediator complex.
引用
收藏
页码:274 / 280
页数:7
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