The effects of frequency in pallidal deep brain stimulation for primary dystonia

被引：54

作者：

Kupsch, A ^{[1
]}

Klaffke, S ^{[1
]}

Kühn, AA ^{[1
]}

Meissner, W ^{[1
]}

Arnold, G ^{[1
]}

Schneider, GH ^{[1
]}

Maier-Hauff, K ^{[1
]}

Trottenberg, T ^{[1
]}

机构：

[1] Humboldt Univ, Charite Campus Virchow, Dept Neurol, D-13353 Berlin, Germany

来源：

JOURNAL OF NEUROLOGY | 2003年 / 250卷 / 10期

关键词：

dystonia; deep brain stimulation; frequency; stimulation parameter; globus pallidus;

D O I：

10.1007/s00415-003-0179-0

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The effect of stimulation frequency for pallidal deep brain stimulation in five patients with either generalized or segmental dystonia was evaluated three to twelve months postoperatively via a randomized, double-blind paradigm. The quality of life and the severity of dystonic symptoms improved by approximately 60% and 43% respectively using a frequency of 130 Hz. Compared with 130 Hz a significant further clinical improvement was observed at frequencies of 180 and 250 Hz, which contrasted with a significant deterioration at lower frequencies (5, 50 Hz) compared to 130 Hz.

引用

页码：1201 / 1205

页数：5

共 17 条

[1]

Bejjani BP, 2000, MOVEMENT DISORD, V15, P919, DOI 10.1002/1531-8257(200009)15:5<919::AID-MDS1024>3.0.CO

[2]

2-0

[3]

Benabid AL, 2001, J Neurol, V248, pIII37, DOI [10.1007/PL00007825, DOI 10.1007/PL00007825]

[4] VALIDITY AND RELIABILITY OF A RATING-SCALE FOR THE PRIMARY TORSION DYSTONIAS [J].

BURKE, RE ;

FAHN, S ;

MARSDEN, CD ;

BRESSMAN, SB ;

MOSKOWITZ, C ;

FRIEDMAN, J .

NEUROLOGY, 1985, 35 (01) :73-77

[5] Treatment of DYT1-generalised dystonia by stimulation of the internal globus pallidus [J].

Coubes, P ;

Roubertie, A ;

Vayssiere, N ;

Hemm, S ;

Echenne, B .

LANCET, 2000, 355 (9222) :2220-2221

[6] Microstimulation-induced inhibition of neuronal firing in human globus pallidus [J].

Dostrovsky, JO ;

Levy, R ;

Wu, JP ;

Hutchison, WD ;

Tasker, RR ;

Lozano, AM .

JOURNAL OF NEUROPHYSIOLOGY, 2000, 84 (01) :570-574

[7] Chronaxie calculated from current-duration and voltage-duration data [J].

Holsheimer, J ;

Dikstra, EA ;

Demeulemeester, H ;

Nuttin, B .

JOURNAL OF NEUROSCIENCE METHODS, 2000, 97 (01) :45-50

[8] Review of the functional surgical treatment of dystonia [J].

Krack, P ;

Vercueil, L .

EUROPEAN JOURNAL OF NEUROLOGY, 2001, 8 (05) :389-399

[9] Modulation of motor cortex excitability by pallidal stimulation in patients with severe dystonia [J].

Kühn, AA ;

Meyer, BU ;

Trottenberg, T ;

Brandt, SA ;

Schneider, GH ;

Kupsch, A .

NEUROLOGY, 2003, 60 (05) :768-774

[10] Globus pallidus deep brain stimulation for generalized dystonia: Clinical and PET investigation [J].

Kumar, R ;

Dagher, A ;

Hutchison, WD ;

Lang, AE ;

Lozano, AM .

NEUROLOGY, 1999, 53 (04) :871-874

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