Complex caged polyisoprenylated benzophenone derivatives, sampsoniones A and B, from Hypericum sampsonii

被引：50

作者：

Hu, LH ^{[1
]}

Sim, KY ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 43期

关键词：

sampsonione A; sampsonione B; polyisoprenylated benzophenone; Hypericum sampsonii; Guttiferae;

D O I：

10.1016/S0040-4039(98)01741-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The aerial parts of the Chinese medicinal plant Hypericum sampsonii yielded two novel metabolites, sampsoniones A and B, which are characterised by their unique tetracyclo-polyketonic core with benzoyl, 3-methyl-2-butenyl and geranyl substituents. Their structures were determined by detailed spectral analysis. Sampsonione A exhibited moderate cytotoxicity to P388 cancer cell line. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7999 / 8002

页数：4

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