Circulating endothelial cells in renal transplant recipients

被引：14

作者：

Mohamed, AS ^{[1
]}

Thomson, J ^{[1
]}

McDonald, KJ ^{[1
]}

Hillyard, DZ ^{[1
]}

Mark, PB ^{[1
]}

Elliott, HL ^{[1
]}

Jardine, AG ^{[1
]}

机构：

[1] Univ Glasgow, Western Infirm, Dept Cardiovasc & Med Sci, Gardiner Inst, Glasgow G11 6NT, Lanark, Scotland

来源：

TRANSPLANTATION PROCEEDINGS | 2005年 / 37卷 / 05期

关键词：

D O I：

10.1016/j.transproceed.2005.03.126

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Circulating endothelial cells (CECs) are a marker of endothelial injury and endothelial dysfunction. We measured CECs in 95 patients with functioning renal transplants at risk of premature cardiovascular (CV) disease and in normal control subjects. We were unable to demonstrate consistent relationships between CEC levels and conventional CV risk factors in transplant recipients. However, CEC levels were increased in patients with a history of rejection. We conclude that CECs are of little use as a marker of CV risk in this population but may be a useful marker to monitor allograft rejection.

引用

页码：2387 / 2390

页数：4

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