Diphtheria in the former Soviet Union: Reemergence of a pandemic disease

被引:146
作者
Vitek, CR [1 ]
Wharton, M [1 ]
机构
[1] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA
关键词
D O I
10.3201/eid0404.980404
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The massive reemergence of diphtheria in the Newly Independent States of the former Soviet Union marked the first large-scale diphtheria epidemic in industrialized countries in 3 decades. Factors contributing to the epidemic included a large population of susceptible adults; decreased childhood immunization, which compromised what had been a well-established childhood vaccination program; suboptimal socioeconomic conditions; and high population movement. The role of a change in the predominant circulating strains of Corynebacterium diphtheriae in this epidemic remains uncertain. Massive, well-coordinated international assistance and unprecedented efforts to vaccinate adults were needed to control the epidemic.
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页码:539 / 550
页数:12
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