Motivations for participating in a clinical trial on an avian influenza vaccine

被引:10
作者
Costas, Laura [1 ,2 ]
Bayas, Jose M. [1 ]
Serrano, Beatriz [1 ,2 ]
Lafuente, Sarah [1 ]
Munoz, M-Amparo [1 ]
机构
[1] Hosp Clin IDIBAPS, Prevent Med & Epidemiol Serv, Adult Vaccinat Ctr, Barcelona, Spain
[2] Catalan Inst Oncol, Canc Epidemiol Res Programme, Unit Infect & Canc, Barcelona, Spain
关键词
Motivations; Clinical trial; Vaccines; Avian influenza; PHASE-I;
D O I
10.1186/1745-6215-13-28
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
In this study we describe the sociodemographic characteristics of people participating in a clinical trial on the safety and immunogenicity of a H5N1 influenza vaccine and we identify the main motivations for joining it.
引用
收藏
页数:4
相关论文
共 11 条
[1]   Why healthy subjects volunteer for phase I studies and how they perceive their participation? [J].
Almeida, Luis ;
Azevedo, Benedita ;
Nunes, Teresa ;
Vaz-da-Silva, Manuel ;
Soares-da-Silva, Patricio .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2007, 63 (11) :1085-1094
[2]   Current concepts - Avian influenza A (H5N1) infection in humans [J].
Beigel, H ;
Farrar, H ;
Han, AM ;
Hayden, FG ;
Hyer, R ;
de Jong, MD ;
Lochindarat, S ;
Tien, NTK ;
Hien, NT ;
Hien, TT ;
Nicoll, A ;
Touch, S ;
Yuen, KY .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (13) :1374-1385
[3]  
Beigel JH, 2006, NEW ENGL J MED, V354, P884
[4]   Barriers and Motivations for Women to Participate in Cardiovascular Trials [J].
Cheung, Angela M. ;
Lee, Yuna ;
Kapral, Moira ;
Scher, Judite ;
Ho, Irene ;
Lui-Yee, Doris ;
Stewart, Donna E. .
JOURNAL OF OBSTETRICS AND GYNAECOLOGY CANADA, 2008, 30 (04) :332-337
[5]   Motivations for participating in an HIV vaccine efficacy trial [J].
Colfax, G ;
Buchbinder, S ;
Vamshidar, G ;
Celum, C ;
McKirnan, D ;
Neidig, J ;
Koblin, B ;
Gurwith, M ;
Bartholow, B .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2005, 39 (03) :359-364
[6]   Hypertensive patients' willingness to participate in placebo-controlled trials: Implications for recruitment efficiency [J].
Halpern, SD ;
Karlawish, JHT ;
Casarett, D ;
Berlin, JA ;
Townsend, RR ;
Asch, DA .
AMERICAN HEART JOURNAL, 2003, 146 (06) :985-992
[7]   Pandemic (H1N1) 2009 influenza in the UK: clinical and epidemiological findings from the first few hundred (FF100) cases [J].
McLean, E. ;
Pebody, R. G. ;
Campbell, C. ;
Chamberland, M. ;
Hawkins, C. ;
Nguyen-Van-Tam, J. S. ;
Oliver, I. ;
Smith, G. E. ;
Ihekweazu, C. ;
Bracebridge, S. ;
Maguire, H. ;
Harris, R. ;
Kafatos, G. ;
White, P. J. ;
Wynne-Evans, E. ;
Green, J. ;
Myers, R. ;
Underwood, A. ;
Dallman, T. ;
Wreghitt, T. ;
Zambon, M. ;
Ellis, J. ;
Phin, N. ;
Smyth, B. ;
McMenamin, J. ;
Watson, J. M. .
EPIDEMIOLOGY AND INFECTION, 2010, 138 (11) :1531-1541
[8]   Patient motivations surrounding participation in phase I and phase II clinical trials of cancer chemotherapy [J].
Nurgat, ZA ;
Craig, W ;
Campbell, NC ;
Bissett, JD ;
Cassidy, J ;
Nicolson, MC .
BRITISH JOURNAL OF CANCER, 2005, 92 (06) :1001-1005
[9]   Safety and reactogenicity profile of an adjuvanted H5N1 pandemic candidate vaccine in adults within a phase III safety trial [J].
Rumke, Hans C. ;
Bayas, Jos-Maria ;
de Juanes, Jose-Ramon ;
Caso, Covadonga ;
Richardus, Jan Hendrik ;
Campins, Magda ;
Rombo, Lars ;
Duval, Xavier ;
Romanenko, Viktor ;
Schwarz, Tino F. ;
Fassakhov, Rustem ;
Abad-Santos, Francisco ;
von Sonnenburg, Frank ;
Drame, Mamadou ;
Sanger, Roland ;
Balloun, W. Ripley .
VACCINE, 2008, 26 (19) :2378-2388
[10]   Vaccines in a hurry [J].
Soborg, Christian ;
Molbak, Kare ;
Doherty, T. Mark ;
Ulleryd, Peter ;
Brooks, Tim ;
Coenen, Claudine ;
van der Zeijst, Ben .
VACCINE, 2009, 27 (25-26) :3295-3298