Profiling brain transcription: neurons learn a lesson from yeast

被引:19
作者
Cao, YX
Dulac, C
机构
[1] Affymetrix Inc, Santa Clara, CA 95051 USA
[2] Harvard Univ, Howard Hughes Med Inst, Cambridge, MA 02138 USA
[3] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA
关键词
D O I
10.1016/S0959-4388(00)00258-0
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The application of microarray technologies to the brain poses unique challenges, because of the complexity of the central nervous system and the availability of resources. Nevertheless, recent studies using DNA chips have made inroads into the molecular characterization of regional and functional brain units, the identification of developmental gene expression patterns, and the discovery of transcriptional differences associated with behavioral and neuropathological traits.
引用
收藏
页码:615 / 620
页数:6
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