Chemokines, lymphocytes and viruses: what goes around, comes around

被引:57
作者
Nelson, PJ
Krensky, AM
机构
[1] Univ Munich, Clin Innenstadt, Med Poliklin, Dept Internal Med, D-80336 Munich, Germany
[2] Stanford Univ, Med Ctr, Dept Pediat, Div Immunol & Transplantat Biol, Stanford, CA 94305 USA
关键词
D O I
10.1016/S0952-7915(98)80164-7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Chemokines are believed to be the long-sought soluble mediators of selective lymphocyte recruitment. As most selectin-integrin interactions are nonselective, it is thought that the discrimination seen during lymphocyte infiltration into tissues is brought about by the actions of distinct chemokines. Developments over the past year have demonstrated the expanding roles of these factors in lymphocyte chemoattraction; normal trafficking, and viral immunity.
引用
收藏
页码:265 / 270
页数:6
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