Separation and determination of quaternary ammonium compounds by high-performance liquid chromatography with a hydrophilic polymer column and conductometric detection

被引：27

作者：

Shibukawa, M

Eto, R

Kira, A

Miura, F

Oguma, K

Tatsumoto, H

Ogura, H

Uchiumi, A

机构：

[1] Nihon Univ, Coll Ind Technol, Dept Ind Chem, Narashino, Chiba 2758575, Japan

[2] Chiba Univ, Fac Engn, Dept Mat Technol, Inage Ku, Chiba 2638522, Japan

[3] Chiba Prefectural Lab Water Pollut, Mihama Ku, Chiba 2610005, Japan

[4] Natl Inst Mat & Chem Res, Dept Analyt Chem, Tsukuba, Ibaraki 3050046, Japan

来源：

JOURNAL OF CHROMATOGRAPHY A | 1999年 / 830卷 / 02期

关键词：

quaternary ammonium compounds;

D O I：

10.1016/S0021-9673(98)00939-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An HPLC method has been developed for separation and determination of long alkyl chain quaternary ammonium compounds. A column packed with a hydrophilic polymer packing, Shodex Asahipak GF-310 HQ, and a water-acetonitrile mixture containing 4,4'-bipyridyl and hydrochloric acid were used to depress hydrophobic adsorption of the quaternary ammonium compounds and increase the sensitivity of the conductometric detection with a micromembrane suppressor. Dodecyltrimethylammonium, cetyltrimethylammonium, tetradecyldimethylbenzylammonium and stearyltrimethylammonium ions can be completely separated from one another and quantified at 0.1 nmol level. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：321 / 328

页数：8

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