Comparison of the standard gamble, rating scale, AQLQ and SF-36 for measuring quality of life in asthma

被引:66
作者
Juniper, EF
Norman, GR
Cox, FM
Roberts, JN
机构
[1] McMaster Univ, Fac Hlth Sci, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada
[2] Glaxo Wellcome Inc, Res Triangle Pk, NC 27709 USA
[3] Univ Western Ontario, Dept Epidemiol & Biostat, London, ON, Canada
关键词
asthma; measurement; quality of life; questionnaires; utilities;
D O I
10.1183/09031936.01.00088301
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
With interest in health economics growing, there is a demand for valid methods for measuring health-related quality of life (HRQL) in asthma using utilities. The aims of this study were to develop disease-specific versions of the standard gamble and rating scale, to compare their measurement properties with those of the Asthma Quality of Life Questionnaire (AQLQ) and the Medical Outcomes Survey Short-Form 36 (SF-36), as well as to determine their validity for assessing asthma-specific quality of life. Forty adults with symptomatic asthma participated in a 9-week observational study. Participants completed the standard gamble, rating scale, AQLQ, SF-36 and other measures of clinical asthma status at baseline and after 1, 5 and 9 weeks. In patients whose asthma was stable between assessments, reliability was good for the rating scale (intraclass correlation coefficient (ICC)=0.89) and the AQLQ (ICC=0.95) but more modest for the SF-36 mental score (ICC=0.68), SF-36 physical score (ICC= 0.65) and standard gamble (ICC=0.59). The responsiveness index was highest in the AQLQ (1.35), followed by the rating scale (0.74), the physical score of the SF-36 (0.61) and the standard gamble (0.31). Construct validity (correlation with other indices of health status) was strongest for the AQLQ and the rating scale. In conclusion, both the disease-specific rating scale and the Asthma Quality of. Life Questionnaire have strong measurement properties for measuring asthma-specific quality of life, the Short-Form 36 health survey physical summary score has more modest properties. Although the disease-specific standard gamble has acceptable discriminative properties, its evaluative properties are too inadequate for it to be used in cost/utility analyses. Poor correlation between the standard gamble and the rating scale indicates that utilities cannot be derived from rating scale data.
引用
收藏
页码:38 / 44
页数:7
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