The epidemiology of gonorrhoea, chlamydial infection and syphilis in four African cities

被引:57
作者
Buvé, A [1 ]
Weiss, HA [1 ]
Laga, M [1 ]
Van Dyck, E [1 ]
Musonda, R [1 ]
Zekeng, L [1 ]
Kahindo, M [1 ]
Anagonou, S [1 ]
Morison, L [1 ]
Robinson, NJ [1 ]
Hayes, RJ [1 ]
机构
[1] Inst Trop Med, Dept Microbiol, STD HIV Res & Intervent Unit, B-2000 Antwerp, Belgium
关键词
epidemiology; syphilis; chlamydial infection; gonorrhoea; Africa;
D O I
10.1097/00002030-200108004-00009
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Objectives: To compare the epidemiology of gonorrhoea, chlamydial infection and syphilis in four cities in sub-Saharan Africa; two with a high prevalence of HIV infection (Kisumu, Kenya and Ndola, Zambia), and two with a relatively low HIV prevalence (Cotonou, Benin and Yaounde, Cameroon). Design: Cross-sectional study, using standardized methods, including a standardized questionnaire and standardized laboratory tests, in four cities in sub-Saharan Africa. Methods: In each city, a random sample of about 2000 adults aged 15-49 years was taken. Consenting men and women were interviewed about their socio-demographic characteristics and their sexual behaviour, and were tested for HIV, syphilis, herpes simplex virus type 2 (HSV-2), gonorrhoea, chlamydial infection, and (women only) Trichomonas vaginalis infection. Risk factor analyses were carried out for chlamydial infection and syphilis seroreactivity. Results: The prevalence of gonorrhoea ranged between 0% in men in Kisumu and 2.7% in women in Yaounde. Men and women in Yaounde had the highest prevalence of chlamydial infection (5.9 and 9.4%, respectively). In the other cities, the prevalence of chlamydial infection ranged between 1.3% in women in Cotonou and 4.5% in women in Kisumu. in Ndola, the prevalence of syphilis seroreactivity was over 10% in both men and women; it was around 6% in Yaounde, 3-4% in Kisumu, and 1-2% in Cotonou. Chlamydial infection was associated with rate of partner change for both men and women, and with young age for women. At the population level, the prevalence of chlamydial infection correlated well with reported rates of partner change. Positive syphilis serology was associated with rate of partner change and with HSV-2 infection. The latter association could be due to biological interaction between syphilis and HSV-2 or to residual confounding by sexual behaviour. At the population level, there was no correlation between prevalence of syphilis seroreactivity and reported rates of partner change Conclusion: Differences in prevalence of chlamydial infection could be explained by differences in reported sexual behaviour, but the variations in prevalence of syphilis seroreactivity remained unexplained. More research is needed to better understand the epidemiology of sexually transmitted infections in Africa. (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码:S79 / S88
页数:10
相关论文
共 24 条
  • [1] Anderson RM., 1999, SEXUALLY TRANSMITTED, P25
  • [2] AGE AND CLINICAL IMMUNITY TO INFECTIONS WITH CHLAMYDIA-TRACHOMATIS
    ARNO, JN
    KATZ, BP
    MCBRIDE, R
    CARTY, GA
    BATTEIGER, BE
    CAINE, VA
    JONES, RB
    [J]. SEXUALLY TRANSMITTED DISEASES, 1994, 21 (01) : 47 - 52
  • [3] Detection of Chlamydia trachomatis and Neisseria gonorrhoeae by ligase chain reaction-based assays with clinical specimens from various sites: Implications for diagnostic testing and screening
    Buimer, M
    VanDoornum, GJJ
    Ching, S
    Peerbooms, PGH
    Plier, PK
    Ram, D
    Lee, HH
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (10) : 2395 - 2400
  • [4] Multicentre study on factors determining differences in rate of spread of HIV in sub-Saharan Africa:: methods and prevalence of HIV infection
    Buvé, A
    Caraël, M
    Hayes, RJ
    Auvert, B
    Ferry, B
    Robinson, NJ
    Anagonou, S
    Kanhonou, L
    Laourou, M
    Abega, S
    Akam, E
    Zekeng, L
    Chege, J
    Kahindo, M
    Rutenberg, N
    Kaona, F
    Musonda, R
    Sukwa, T
    Morison, L
    Weiss, HA
    Laga, M
    [J]. AIDS, 2001, 15 : S5 - S14
  • [5] The epidemiology of trichomoniasis in women in four African cities
    Buvé, A
    Weiss, HA
    Laga, M
    Van Dyck, E
    Musonda, R
    Zekeng, L
    Kahindo, M
    Anagonou, S
    Morison, L
    Robinson, NJ
    Hayes, RJ
    [J]. AIDS, 2001, 15 : S89 - S96
  • [6] DESCHRYVER A, 1990, B WORLD HEALTH ORGAN, V68, P639
  • [7] Comparison of key parameters of sexual behaviour in four African urban populations with different levels of HIV infection
    Ferry, B
    Caraël, M
    Buvé, A
    Auvert, B
    Laourou, M
    Kanhonou, L
    de Loenzien, M
    Akam, E
    Chege, J
    Kaona, F
    [J]. AIDS, 2001, 15 : S41 - S50
  • [8] From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection
    Fleming, DT
    Wasserheit, JN
    [J]. SEXUALLY TRANSMITTED INFECTIONS, 1999, 75 (01) : 3 - 17
  • [9] GOEMAN J, 1995, GENITOURIN MED, V71, P275
  • [10] Han Y, 1993, J Community Health, V18, P1, DOI 10.1007/BF01321516