Endogenous Lentiviruses in the Ferret Genome

被引:34
作者
Cui, Jie [1 ]
Holmes, Edward C. [1 ,2 ]
机构
[1] Penn State Univ, Dept Biol, Ctr Infect Dis Dynam, University Pk, PA 16802 USA
[2] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
PHYLOGENIES; PRIMATE;
D O I
10.1128/JVI.06652-11
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
By screening 74 chordate genomes for endogenous lentiviruses using Pol sequences of exogenous lentiviruses as a reference, we identified a novel endogenous lentivirus in the genome of the ferret (Mustela putorius furo). Phylogenetic analysis suggested that the ferret endogenous lentivirus, denoted ELVmpf, diverged early in the evolution of the mammalian lentiviruses, although with a lack of resolution at key nodes. These data support the notion that lentiviruses have evolved on timescales of millions of years.
引用
收藏
页码:3383 / 3385
页数:3
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